Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity

Series of novel acyclic nucleoside phosphonates (ANPs) with various nucleobases and 2-(2-phosphonoethoxy)ethyl (PEE) chain bearing various substituents in β-position to the phosphonate moiety were prepared. The influence of structural alternations on antiviral activity was studied. Several derivativ...

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Detalles Bibliográficos
Autores principales: Hocková, Dana, Holý, Antonín, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125515/
https://www.ncbi.nlm.nih.gov/pubmed/21745746
http://dx.doi.org/10.1016/j.bmc.2011.06.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125515/
https://www.ncbi.nlm.nih.gov/pubmed/21745746
http://dx.doi.org/10.1016/j.bmc.2011.06.045

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