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Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity

Series of novel acyclic nucleoside phosphonates (ANPs) with various nucleobases and 2-(2-phosphonoethoxy)ethyl (PEE) chain bearing various substituents in β-position to the phosphonate moiety were prepared. The influence of structural alternations on antiviral activity was studied. Several derivativ...

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Detalles Bibliográficos
Autores principales:	Hocková, Dana, Holý, Antonín, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125515/ https://www.ncbi.nlm.nih.gov/pubmed/21745746 http://dx.doi.org/10.1016/j.bmc.2011.06.045

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