Broad-spectrum activity of 8-chloro-7-deazaguanosine against RNA virus infections in mice and rats

A novel nucleoside analog, 8-chloro-7-deazaguanosine (8-Cl-7-dzGuo), was evaluated for anti-RNA virus activity in rodents in parallel with the related compound 7-deaza-7-thia-8-oxoguanosine (7-dzTOGuo). Half-daily intraperitoneal (i.p.) doses of each substance administered 24 and 18 h prior to i.p....

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Detalles Bibliográficos
Autores principales: Smee, Donald F., Alaghamandan, Hassan A., Ramasamy, Kandasamy, Revankar, Ganapathi R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125532/
https://www.ncbi.nlm.nih.gov/pubmed/7605116
http://dx.doi.org/10.1016/0166-3542(94)00084-L

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125532/
https://www.ncbi.nlm.nih.gov/pubmed/7605116
http://dx.doi.org/10.1016/0166-3542(94)00084-L

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