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Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design
The main proteinase of SARS-associated coronavirus (SARS-CoV) plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development. The important thing is to understand its binding mechanism with possible ligands. In this study, we investigated p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125554/ https://www.ncbi.nlm.nih.gov/pubmed/15080921 http://dx.doi.org/10.1016/j.bmc.2004.02.015 |