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Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design

The main proteinase of SARS-associated coronavirus (SARS-CoV) plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development. The important thing is to understand its binding mechanism with possible ligands. In this study, we investigated p...

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Detalles Bibliográficos
Autores principales: Zhang, Xue Wu, Yap, Yee Leng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125554/
https://www.ncbi.nlm.nih.gov/pubmed/15080921
http://dx.doi.org/10.1016/j.bmc.2004.02.015