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5′-O-Masked 2′-deoxyadenosine analogues as lead compounds for hepatitis C virus (HCV) therapeutic agents

On the basis of our previous study on antiviral agents against the severe acute respiratory syndrome (SARS) coronavirus, a series of nucleoside analogues whose 5′-hydroxyl groups are masked by various protective groups such as carboxylate, sulfonate, and ether were synthesized and evaluated to devel...

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Detalles Bibliográficos
Autores principales: Ikejiri, Masahiro, Ohshima, Takayuki, Kato, Keizo, Toyama, Masaaki, Murata, Takayuki, Shimotohno, Kunitada, Maruyama, Tokumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125560/
https://www.ncbi.nlm.nih.gov/pubmed/17766124
http://dx.doi.org/10.1016/j.bmc.2007.08.025