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Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures()
Peripheral T cells can be polarized towards type 1 or type 2 cytokine immune responses during TCR engagement. Because T cell selection by peptide plus self-MHC in the thymus requires TCR engagement, we hypothesized that type 1 cytokines may polarize developing T cells. We cultured thymi from BBDR ra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd.
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125593/ https://www.ncbi.nlm.nih.gov/pubmed/12604310 http://dx.doi.org/10.1016/S0896-8411(02)00091-4 |