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Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures()

Peripheral T cells can be polarized towards type 1 or type 2 cytokine immune responses during TCR engagement. Because T cell selection by peptide plus self-MHC in the thymus requires TCR engagement, we hypothesized that type 1 cytokines may polarize developing T cells. We cultured thymi from BBDR ra...

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Detalles Bibliográficos
Autores principales:	Whalen, Barbara J, Marounek, Jan, Mordes, John P, Rossini, Aldo A, Greiner, Dale L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd. 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125593/ https://www.ncbi.nlm.nih.gov/pubmed/12604310 http://dx.doi.org/10.1016/S0896-8411(02)00091-4

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