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Mucosal and systemic immune responses elicited by recombinant Lactococcus lactis expressing a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis()

We constructed a food-grade expression system harboring a F1S1 fusion protein of Bordetella pertussis to be produced in Lactococcus lactis NZ3900 as a new oral vaccine model against whooping cough, caused by B. pertussis. F1S1 was composed of N-terminally truncated S1 subunit of pertussis toxin and...

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Detalles Bibliográficos
Autores principales: Torkashvand, Ali, Bahrami, Fariborz, Adib, Minoo, Ajdary, Soheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125623/
https://www.ncbi.nlm.nih.gov/pubmed/29738814
http://dx.doi.org/10.1016/j.micpath.2018.05.008