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Detection of ubiquitin–proteasome enzymatic activities in cells: Application of activity-based probes to inhibitor development()
Background: Synthetic probes that mimic natural substrates can enable the detection of enzymatic activities in a cellular environment. One area where such activity-based probes have been applied is the ubiquitin–proteasome pathway, which is emerging as an important therapeutic target. A family of re...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125640/ https://www.ncbi.nlm.nih.gov/pubmed/22613766 http://dx.doi.org/10.1016/j.bbamcr.2012.05.014 |