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Detection of ubiquitin–proteasome enzymatic activities in cells: Application of activity-based probes to inhibitor development()

Background: Synthetic probes that mimic natural substrates can enable the detection of enzymatic activities in a cellular environment. One area where such activity-based probes have been applied is the ubiquitin–proteasome pathway, which is emerging as an important therapeutic target. A family of re...

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Detalles Bibliográficos
Autores principales: Kramer, Holger B., Nicholson, Benjamin, Kessler, Benedikt M., Altun, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125640/
https://www.ncbi.nlm.nih.gov/pubmed/22613766
http://dx.doi.org/10.1016/j.bbamcr.2012.05.014

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