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Synthetic and semi-synthetic strategies to study ubiquitin signaling

The post-translational modification ubiquitin can be attached to the ɛ-amino group of lysine residues or to a protein's N-terminus as a mono ubiquitin moiety. Via its seven intrinsic lysine residues and its N-terminus, it can also form ubiquitin chains on substrates in many possible ways. To st...

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Detalles Bibliográficos
Autores principales: van Tilburg, Gabriëlle BA, Elhebieshy, Angela F, Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125694/
https://www.ncbi.nlm.nih.gov/pubmed/27315041
http://dx.doi.org/10.1016/j.sbi.2016.05.022