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Cholesterol: fa(s)t-food for enterovirus genome replication

Hijacking and remodeling of host membranes is an obligatory step in the replicative cycle of (+)RNA viruses, including enteroviruses. Ilnytska et al. unveiled in Cell Host & Microbe that enteroviruses usurp clathrin-mediated endocytosis to shuttle cholesterol to sites of genome replication and t...

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Detalles Bibliográficos
Autores principales: Strating, Jeroen R.P., van der Schaar, Hilde M., van Kuppeveld, Frank J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125759/
https://www.ncbi.nlm.nih.gov/pubmed/24103385
http://dx.doi.org/10.1016/j.tim.2013.09.007