Cholesterol: fa(s)t-food for enterovirus genome replication

Hijacking and remodeling of host membranes is an obligatory step in the replicative cycle of (+)RNA viruses, including enteroviruses. Ilnytska et al. unveiled in Cell Host & Microbe that enteroviruses usurp clathrin-mediated endocytosis to shuttle cholesterol to sites of genome replication and t...

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Autores principales: Strating, Jeroen R.P., van der Schaar, Hilde M., van Kuppeveld, Frank J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125759/
https://www.ncbi.nlm.nih.gov/pubmed/24103385
http://dx.doi.org/10.1016/j.tim.2013.09.007
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author Strating, Jeroen R.P.
van der Schaar, Hilde M.
van Kuppeveld, Frank J.M.
author_facet Strating, Jeroen R.P.
van der Schaar, Hilde M.
van Kuppeveld, Frank J.M.
author_sort Strating, Jeroen R.P.
collection PubMed
description Hijacking and remodeling of host membranes is an obligatory step in the replicative cycle of (+)RNA viruses, including enteroviruses. Ilnytska et al. unveiled in Cell Host & Microbe that enteroviruses usurp clathrin-mediated endocytosis to shuttle cholesterol to sites of genome replication and that cholesterol is needed for efficient replication.
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spelling pubmed-71257592020-04-08 Cholesterol: fa(s)t-food for enterovirus genome replication Strating, Jeroen R.P. van der Schaar, Hilde M. van Kuppeveld, Frank J.M. Trends Microbiol Article Hijacking and remodeling of host membranes is an obligatory step in the replicative cycle of (+)RNA viruses, including enteroviruses. Ilnytska et al. unveiled in Cell Host & Microbe that enteroviruses usurp clathrin-mediated endocytosis to shuttle cholesterol to sites of genome replication and that cholesterol is needed for efficient replication. Elsevier Ltd. 2013-11 2013-10-06 /pmc/articles/PMC7125759/ /pubmed/24103385 http://dx.doi.org/10.1016/j.tim.2013.09.007 Text en Copyright © 2013 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Strating, Jeroen R.P.
van der Schaar, Hilde M.
van Kuppeveld, Frank J.M.
Cholesterol: fa(s)t-food for enterovirus genome replication
title Cholesterol: fa(s)t-food for enterovirus genome replication
title_full Cholesterol: fa(s)t-food for enterovirus genome replication
title_fullStr Cholesterol: fa(s)t-food for enterovirus genome replication
title_full_unstemmed Cholesterol: fa(s)t-food for enterovirus genome replication
title_short Cholesterol: fa(s)t-food for enterovirus genome replication
title_sort cholesterol: fa(s)t-food for enterovirus genome replication
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125759/
https://www.ncbi.nlm.nih.gov/pubmed/24103385
http://dx.doi.org/10.1016/j.tim.2013.09.007
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