Emergence of a coronavirus infectious bronchitis virus mutant with a truncated 3b gene: functional characterization of the 3b protein in pathogenesis and replication

The subgenomic RNA 3 of IBV has been shown to be a tricistronic mRNA, encoding three products in IBV-infected cells. To explore if the least expressed ORF, ORF 3b, which encodes a nonstructural protein, is evolutionarily conserved and functionally indispensable for viral propagation in cultured cell...

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Detalles Bibliográficos
Autores principales: Shen, S, Wen, Z.L, Liu, D.X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science (USA). 2003
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125764/
https://www.ncbi.nlm.nih.gov/pubmed/12832199
http://dx.doi.org/10.1016/S0042-6822(03)00117-X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125764/
https://www.ncbi.nlm.nih.gov/pubmed/12832199
http://dx.doi.org/10.1016/S0042-6822(03)00117-X

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