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Budding Yeast SKP1 Encodes an Evolutionarily Conserved Kinetochore Protein Required for Cell Cycle Progression

The budding yeast SKP1gene, identified as a dosage suppressor of a known kinetochore protein mutant, encodes an intrinsic 22.3 kDa subunit of CBF3, a multiprotein complex that binds centromere DNA in vitro. Temperature-sensitive mutations in SKP1 define two distinct phenotypic classes. skp1-4 mutant...

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Detalles Bibliográficos
Autores principales: Connelly, Carla, Hieter, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press. 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125826/
https://www.ncbi.nlm.nih.gov/pubmed/8706132
http://dx.doi.org/10.1016/S0092-8674(00)80099-9