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Characterization of a novel live attenuated infectious bronchitis virus vaccine candidate derived from a Korean nephropathogenic strain

A nephropathogenic K2/01 strain of infectious bronchitis virus (IBV) was attenuated by 170 serial passages in embryonated chicken eggs for possible use as a future IBV vaccine strain. High-growth properties and narrow tissue tropisms (limited replication in respiratory tracts) were achieved by the a...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Jeong, Youn, Ha Na, Kwon, Ji Sun, Lee, Youn Jeong, Kim, Jae Hong, Lee, Joong Bok, Park, Seung Yong, Choi, In Soo, Song, Chang Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125847/
https://www.ncbi.nlm.nih.gov/pubmed/20153350
http://dx.doi.org/10.1016/j.vaccine.2010.01.062