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Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs

The synthesis of several (3-noradamantyl)amines, [(3-noradamantyl)methyl]amines, (3,7-dimethyl-1-bisnoradamantyl)amines, and [(3,7-dimethyl-1-bisnoradamantyl)methyl]amines is reported. They were evaluated against a wide range of viruses and one of them inhibited the cytopathicity of influenza A viru...

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Detalles Bibliográficos
Autores principales: Camps, Pelayo, Duque, María D., Vázquez, Santiago, Naesens, Lieve, Clercq, Erik De, Sureda, Francesc X., López-Querol, Marta, Camins, Antoni, Pallàs, Mercè, Prathalingam, S. Radhika, Kelly, John M., Romero, Vanessa, Ivorra, Dolores, Cortés, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125889/
https://www.ncbi.nlm.nih.gov/pubmed/18954995
http://dx.doi.org/10.1016/j.bmc.2008.10.028