A multivalent HIV-1 fusion inhibitor based on small helical foldamers

The peptide sequence AcNH–TEG–Glu-Aib-Trp-AibAib-Trp-AibAib-Ile-Asp–OH (1), designed to display the WWI epitope found near the C-terminus of gp41, an envelope glycoprotein decorating the surface of the HIV-1 virus, has been synthesized and proved to have a relevant content of helical conformation be...

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Detalles Bibliográficos
Autores principales: Guarise, Cristian, Shinde, Sandip, Kibler, Karen, Ghirlanda, Giovanna, Prins, Leonard J., Scrimin, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125900/
https://www.ncbi.nlm.nih.gov/pubmed/32287423
http://dx.doi.org/10.1016/j.tet.2012.03.078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125900/
https://www.ncbi.nlm.nih.gov/pubmed/32287423
http://dx.doi.org/10.1016/j.tet.2012.03.078

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