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Compartmentalized intrathecal immunoglobulin synthesis during HIV infection — A model of chronic CNS inflammation?

HIV infects the central nervous system (CNS) during primary infection and persists in resident macrophages. CNS infection initiates a strong local immune response that fails to control the virus but is responsible for by-stander lesions involved in neurocognitive disorders. Although highly active an...

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Detalles Bibliográficos
Autores principales: Bonnan, Mickael, Barroso, Bruno, Demasles, Stéphanie, Krim, Elsa, Marasescu, Raluca, Miquel, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125908/
https://www.ncbi.nlm.nih.gov/pubmed/26198917
http://dx.doi.org/10.1016/j.jneuroim.2015.05.015