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Compartmentalized intrathecal immunoglobulin synthesis during HIV infection — A model of chronic CNS inflammation?
HIV infects the central nervous system (CNS) during primary infection and persists in resident macrophages. CNS infection initiates a strong local immune response that fails to control the virus but is responsible for by-stander lesions involved in neurocognitive disorders. Although highly active an...
Autores principales: | Bonnan, Mickael, Barroso, Bruno, Demasles, Stéphanie, Krim, Elsa, Marasescu, Raluca, Miquel, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125908/ https://www.ncbi.nlm.nih.gov/pubmed/26198917 http://dx.doi.org/10.1016/j.jneuroim.2015.05.015 |
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