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Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of l-ascorbic or imino-l-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations

Keeping the potential synergy of biological activity of synthetic anomalous derivatives of deazapurines and l-ascorbic acid (l-AA) in mind, we have synthesized new 3-, 7- and 9-deazapurine derivatives of l-ascorbic (1–4, 8–10, 13–15) and imino-l-ascorbic acid (5–7, 11, 12, 16–19). These novel compou...

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Detalles Bibliográficos
Autores principales: Stipković Babić, Maja, Makuc, Damjan, Plavec, Janez, Martinović, Tamara, Kraljević Pavelić, Sandra, Pavelić, Krešimir, Snoeck, Robert, Andrei, Graciela, Schols, Dominique, Wittine, Karlo, Mintas, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125971/
https://www.ncbi.nlm.nih.gov/pubmed/26291038
http://dx.doi.org/10.1016/j.ejmech.2015.08.008