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Pacing a small cage: mutation and RNA viruses

RNA viruses have an extremely high mutation rate, and we argue that the most plausible explanation for this is a trade-off with replication speed. We suggest that research into further increasing this mutation rate artificially as an antiviral treatment requires a theoretical reevaluation, especiall...

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Detalles Bibliográficos
Autores principales: Belshaw, Robert, Gardner, Andy, Rambaut, Andrew, Pybus, Oliver G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125972/
https://www.ncbi.nlm.nih.gov/pubmed/18295930
http://dx.doi.org/10.1016/j.tree.2007.11.010