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Pacing a small cage: mutation and RNA viruses
RNA viruses have an extremely high mutation rate, and we argue that the most plausible explanation for this is a trade-off with replication speed. We suggest that research into further increasing this mutation rate artificially as an antiviral treatment requires a theoretical reevaluation, especiall...
Autores principales: | Belshaw, Robert, Gardner, Andy, Rambaut, Andrew, Pybus, Oliver G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125972/ https://www.ncbi.nlm.nih.gov/pubmed/18295930 http://dx.doi.org/10.1016/j.tree.2007.11.010 |
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