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Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro

This report describes the application of real-time PCR for testing antivirals against highly pathogenic viruses such as Lassa virus, SARS coronavirus and Ebola virus. The test combines classical cell culture with a quantitative real-time PCR read-out. The assay for Lassa virus was validated with rib...

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Detalles Bibliográficos
Autores principales: Günther, Stephan, Asper, Marcel, Röser, Christina, Luna, Luciano K.S., Drosten, Christian, Becker-Ziaja, Beate, Borowski, Peter, Chen, Huan-Ming, Hosmane, Ramachandra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126008/
https://www.ncbi.nlm.nih.gov/pubmed/15451189
http://dx.doi.org/10.1016/j.antiviral.2004.05.001