Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors

Quercetin-3-O-amino acid-esters, a new type of quercetin derivatives, were successfully prepared for the first time. Different from quercetin, the novel compounds show higher selectivity as inhibitors against Src tyrosine kinase (IC(50) values ranging from 3.2 μM to 9.9 μM) than against EGFR tyrosin...

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Detalles Bibliográficos
Autores principales: Huang, He, Jia, Qi, Ma, Jingui, Qin, Guangrong, Chen, Yingyi, Xi, Yonghua, Lin, Liping, Zhu, Weiliang, Ding, Jian, Jiang, Hualiang, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126139/
https://www.ncbi.nlm.nih.gov/pubmed/19041163
http://dx.doi.org/10.1016/j.ejmech.2008.09.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126139/
https://www.ncbi.nlm.nih.gov/pubmed/19041163
http://dx.doi.org/10.1016/j.ejmech.2008.09.051

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