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Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2
Deubiquitinating proteases reverse protein ubiquitination and rescue their target proteins from destruction by the proteasome. USP2, a cysteine protease and a member of the ubiquitin specific protease family, is overexpressed in prostate cancer and stabilizes fatty acid synthase, which has been asso...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126176/ https://www.ncbi.nlm.nih.gov/pubmed/16905103 http://dx.doi.org/10.1016/j.str.2006.06.012 |