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Synthesis of N-methyl-d-ribopyranuronamide nucleosides

The synthesis of N-methyl-d-ribopyranuronamide nucleosides is described. The key route is the rearrangement of a 1,2-O-isopropylidene protected furanose sugar with a carboxamide function in the 4-position to a ribopyranuronamide ring. The Lewis acid catalyzed condensation of adenine and thymine nucl...

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Detalles Bibliográficos
Autores principales: Yang, Shiqiong, Busson, Roger, Herdewijn, Piet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126205/
https://www.ncbi.nlm.nih.gov/pubmed/32287418
http://dx.doi.org/10.1016/j.tet.2008.08.027