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Structure–activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors

Human rhinovirus 3C protease (HRV 3C(pro)) is known to be a promising target for development of therapeutic agents against the common cold because of the importance of the protease in viral replication as well as its expression in a large number of serotypes. To explore non-peptidic inhibitors of HR...

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Detalles Bibliográficos
Autores principales: Im, Isak, Lee, Eui Seung, Choi, Soo Jeong, Lee, Ju-Yeon, Kim, Yong-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126291/
https://www.ncbi.nlm.nih.gov/pubmed/19464175
http://dx.doi.org/10.1016/j.bmcl.2009.04.114