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Nipah virus fusion protein: Influence of cleavage site mutations on the cleavability by cathepsin L, trypsin and furin

Nipah virus (NiV), a highly pathogenic member of the Paramyxoviridae which originated from bats, encodes for a fusion (F) protein which is proteolytically processed within endosomes by cathepsin L. We show here that sequence requirements for NiV F activation differ markedly from other para- or ortho...

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Detalles Bibliográficos
Autores principales: Diederich, Sandra, Dietzel, Erik, Maisner, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126315/
https://www.ncbi.nlm.nih.gov/pubmed/19665506
http://dx.doi.org/10.1016/j.virusres.2009.07.020