Mouse hepatitis virus neurovirulence: evidence of a linkage between S glycoprotein expression and immunopathology

Differences in disease outcome between the highly neurovirulent MHV-JHM and mildly neurovirulent MHV-A59 have been attributed to variations within the spike (S) glycoprotein. Previously, we found that MHV-JHM neurovirulence was marked by diminished expression of interferon-γ (IFN-γ) mRNA and a reduc...

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Detalles Bibliográficos
Autores principales: Rempel, Julia D., Murray, Shannon J., Meisner, Jeffrey, Buchmeier, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126387/
https://www.ncbi.nlm.nih.gov/pubmed/14972534
http://dx.doi.org/10.1016/j.virol.2003.08.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126387/
https://www.ncbi.nlm.nih.gov/pubmed/14972534
http://dx.doi.org/10.1016/j.virol.2003.08.041

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