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Mouse hepatitis virus neurovirulence: evidence of a linkage between S glycoprotein expression and immunopathology
Differences in disease outcome between the highly neurovirulent MHV-JHM and mildly neurovirulent MHV-A59 have been attributed to variations within the spike (S) glycoprotein. Previously, we found that MHV-JHM neurovirulence was marked by diminished expression of interferon-γ (IFN-γ) mRNA and a reduc...
Autores principales: | Rempel, Julia D., Murray, Shannon J., Meisner, Jeffrey, Buchmeier, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126387/ https://www.ncbi.nlm.nih.gov/pubmed/14972534 http://dx.doi.org/10.1016/j.virol.2003.08.041 |
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