2-Substituted benzoxazinone analogues as anti-human coronavirus (anti-HCoV) and ICAM-1 expression inhibition agents

A series of 2-substituted benzoxazinones were synthesized and subjected to anti-human coronavirus and ICAM-1 expression inhibition assays. Among them, compounds 1, 3, 4, 5, 6, and 7 exhibited significant anti-HCoV activities, and the IC(50) value of these compounds are 6.08, 5.06, 6.83, 1.92, 7.59,...

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Detalles Bibliográficos
Autores principales: Hsieh, Pei-Wen, Chang, Fang-Rong, Chang, Cheng-Hsien, Cheng, Pei-Wen, Chiang, Lien-Chai, Zeng, Fu-Long, Lin, Kuei-Hsiang, Wu, Yang-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126427/
https://www.ncbi.nlm.nih.gov/pubmed/15324901
http://dx.doi.org/10.1016/j.bmcl.2004.06.083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126427/
https://www.ncbi.nlm.nih.gov/pubmed/15324901
http://dx.doi.org/10.1016/j.bmcl.2004.06.083

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