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Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement

An intradermal injection of Freund's incomplete adjuvant oil (FIA) without further additives was shown to induce erosive polyarthritis in dark Agouti (DA) rats, but not in Lewis rats. Histological examination revealed joint inflammation, first with polymorphonuclear cells and synovial hyperplas...

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Detalles Bibliográficos
Autores principales: Kleinau, Sandra, Erlandsson, Helena, Holmdahl, Rikard, Klareskog, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126449/
https://www.ncbi.nlm.nih.gov/pubmed/1812893
http://dx.doi.org/10.1016/0896-8411(91)90050-M