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Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement
An intradermal injection of Freund's incomplete adjuvant oil (FIA) without further additives was shown to induce erosive polyarthritis in dark Agouti (DA) rats, but not in Lewis rats. Histological examination revealed joint inflammation, first with polymorphonuclear cells and synovial hyperplas...
Autores principales: | Kleinau, Sandra, Erlandsson, Helena, Holmdahl, Rikard, Klareskog, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126449/ https://www.ncbi.nlm.nih.gov/pubmed/1812893 http://dx.doi.org/10.1016/0896-8411(91)90050-M |
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