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Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions

Cell-penetrating peptides (CPPs) are short cationic peptides that have been extensively studied as drug delivery vehicles for proteins, nucleic acids and nanoparticles. However, the formulation of CPP-based therapeutics into different pharmaceutical formulations and their stability in relevant biolo...

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Detalles Bibliográficos
Autores principales: Ezzat, Kariem, Zaghloul, Eman M., EL Andaloussi, Samir, Lehto, Taavi, El-Sayed, Ramy, Magdy, Tarek, Smith, C.I. Edvard, Langel, Ülo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126485/
https://www.ncbi.nlm.nih.gov/pubmed/22698942
http://dx.doi.org/10.1016/j.jconrel.2012.06.006