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Identification of essential components of the S. cerevisiae kinetochore

We have designed and utilized two in vivo assays of kinetochore integrity in S. cerevisiae. One assay detects relaxation of a transcription block formed at centromeres; the other detects an increase in the mitotic stability of a dicentric test chromosome. ctf13-30 and ctf14-42 were identified as put...

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Detalles Bibliográficos
Autores principales: Doheny, Kimberly Floy, Sorger, Peter K., Hyman, Anthony A., Tugendreich, Stuart, Spencer, Forrest, Hieter, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126583/
https://www.ncbi.nlm.nih.gov/pubmed/8500169
http://dx.doi.org/10.1016/0092-8674(93)90255-O