Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

The crystal structure of griffithsin, an antiviral lectin from the red alga Griffithsia sp., was solved and refined at 1.3 Å resolution for the free protein and 0.94 Å for a complex with mannose. Griffithsin molecules form a domain-swapped dimer, in which two β strands of one molecule complete a β p...

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Detalles Bibliográficos
Autores principales: Ziółkowska, Natasza E., O'Keefe, Barry R., Mori, Toshiyuki, Zhu, Charles, Giomarelli, Barbara, Vojdani, Fakhrieh, Palmer, Kenneth E., McMahon, James B., Wlodawer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126681/
https://www.ncbi.nlm.nih.gov/pubmed/16843894
http://dx.doi.org/10.1016/j.str.2006.05.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126681/
https://www.ncbi.nlm.nih.gov/pubmed/16843894
http://dx.doi.org/10.1016/j.str.2006.05.017

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