Toward the discovery of dual HCMV–VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides

The need for novel therapeutic options to fight herpesvirus infections still persists. Herein we report the design, synthesis and antiviral evaluation of a new family of non-nucleoside antivirals, derived from 1-[ω-(4-bromophenoxy)alkyl]uracil derivatives – previously reported inhibitors of human cy...

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Detalles Bibliográficos
Autores principales: Babkov, Denis A., Khandazhinskaya, Anastasia L., Chizhov, Alexander O., Andrei, Graciela, Snoeck, Robert, Seley-Radtke, Katherine L., Novikov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126728/
https://www.ncbi.nlm.nih.gov/pubmed/26443550
http://dx.doi.org/10.1016/j.bmc.2015.09.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126728/
https://www.ncbi.nlm.nih.gov/pubmed/26443550
http://dx.doi.org/10.1016/j.bmc.2015.09.033

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