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5′-Hydroxy-5′-homoaristeromycin: Synthesis and antiviral properties
Synthetically combining the C-4′ side-chain structural features of the antiviral candidates 5′-methylaristeromycin and 5′-homoaristeromycin into a diastereomeric pair of C-4′ side-chain dihydroxylated aristeromycins (6 and 7) is reported. Broad antiviral analyses of the both targets found promising...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126772/ https://www.ncbi.nlm.nih.gov/pubmed/29628328 http://dx.doi.org/10.1016/j.bmcl.2018.03.088 |