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5′-Hydroxy-5′-homoaristeromycin: Synthesis and antiviral properties

Synthetically combining the C-4′ side-chain structural features of the antiviral candidates 5′-methylaristeromycin and 5′-homoaristeromycin into a diastereomeric pair of C-4′ side-chain dihydroxylated aristeromycins (6 and 7) is reported. Broad antiviral analyses of the both targets found promising...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Liu, Chong, Bowlin, Terry L., Schneller, Stewart W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126772/
https://www.ncbi.nlm.nih.gov/pubmed/29628328
http://dx.doi.org/10.1016/j.bmcl.2018.03.088