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Evaluating enzyme activities and structures of DUBs

Ubiquitin signaling requires tight control of all aspects of protein ubiquitination, including the timing, locale, extent, and type of modification. Dysregulation of any of these signaling features can lead to severe human disease. One key mode of regulation is through the controlled removal of the...

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Detalles Bibliográficos
Autores principales: Pruneda, Jonathan N., Komander, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126802/
https://www.ncbi.nlm.nih.gov/pubmed/30850058
http://dx.doi.org/10.1016/bs.mie.2019.01.001