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Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents
Nucleoside analogues that have 6-chloropurine as the nucleobase were synthesized and evaluated for anti-SARS-CoV activity by plaque reduction and yield reduction assays in order to develop novel anti-SARS-CoV agents. Among these analogues, two compounds, namely, 1 and 11, exhibited promising anti-SA...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126875/ https://www.ncbi.nlm.nih.gov/pubmed/17336519 http://dx.doi.org/10.1016/j.bmcl.2007.02.026 |