Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation

Local delivery of small interfering RNA (siRNA) to the lungs constitutes a promising new area in drug delivery. The present study evaluated parameters of importance for spray drying of siRNA-loaded poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles (NPs) into nanocomposite microparticles intended f...

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Detalles Bibliográficos
Autores principales: Jensen, Ditte Marie Krohn, Cun, Dongmei, Maltesen, Morten Jonas, Frokjaer, Sven, Nielsen, Hanne Mørck, Foged, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126878/
https://www.ncbi.nlm.nih.gov/pubmed/19840823
http://dx.doi.org/10.1016/j.jconrel.2009.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126878/
https://www.ncbi.nlm.nih.gov/pubmed/19840823
http://dx.doi.org/10.1016/j.jconrel.2009.10.010

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