Cargando…

Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation

Local delivery of small interfering RNA (siRNA) to the lungs constitutes a promising new area in drug delivery. The present study evaluated parameters of importance for spray drying of siRNA-loaded poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles (NPs) into nanocomposite microparticles intended f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jensen, Ditte Marie Krohn, Cun, Dongmei, Maltesen, Morten Jonas, Frokjaer, Sven, Nielsen, Hanne Mørck, Foged, Camilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126878/ https://www.ncbi.nlm.nih.gov/pubmed/19840823 http://dx.doi.org/10.1016/j.jconrel.2009.10.010

Ejemplares similares

Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery
por: Zimmermann, Christoph M, et al.
Publicado: (2022)

Preparation of siRNA–PLGA/Fabʹ–PLGA mixed micellar system with target cell-specific recognition
por: Hazekawa, Mai, et al.
Publicado: (2021)

Simultaneous Spray Drying for Combination Dry Powder Inhaler Formulations
por: Shepard, Kimberly B., et al.
Publicado: (2022)

Spray-dried powders enhance vaginal siRNA delivery by potentially modulating the mucus molecular sieve structure
por: Wu, Na, et al.
Publicado: (2015)

Chitosan Oleate Coated PLGA Nanoparticles as siRNA Drug Delivery System
por: Miele, Dalila, et al.
Publicado: (2021)

Manipulation of Spray-Drying Conditions to Develop an Inhalable Ivermectin Dry Powder
por: Saha, Tushar, et al.
Publicado: (2022)

Development of dry powder inhaler containing tadalafil-loaded PLGA nanoparticles
por: Varshosaz, Jaleh, et al.
Publicado: (2017)

An Overview on Spray-Drying of Protein-Loaded Polymeric Nanoparticles for Dry Powder Inhalation
por: Marante, Tânia, et al.
Publicado: (2020)

Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model
por: Bohr, Adam, et al.
Publicado: (2020)

Spray Dried Formulations for Inhalation—Meaningful Characterisation of Powder Properties
por: Jüptner, Angelika, et al.
Publicado: (2019)

Amorphicity and Aerosolization of Soluplus-Based Inhalable Spray Dried Powders
por: Adhikari, Bishal Raj, et al.
Publicado: (2022)

Development of Inhalable Spray Dried Nitrofurantoin Formulations for the Treatment of Emphysema
por: Leslie, Mathew N., et al.
Publicado: (2022)

Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles
por: Lokras, Abhijeet, et al.
Publicado: (2021)

Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying
por: Okuda, Tomoyuki, et al.
Publicado: (2015)

Screening of Cyclodextrins in the Processing of Buserelin Dry Powders for Inhalation Prepared by Spray Freeze-Drying
por: Rostamnezhad, Mostafa, et al.
Publicado: (2023)

Spray-Dried Powder Formulation of Capreomycin Designed for Inhaled Tuberculosis Therapy
por: Shao, Zitong, et al.
Publicado: (2021)

Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation
por: Wu, Xiao, et al.
Publicado: (2013)

Formulation of inhalable lipid-based salbutamol sulfate microparticles by spray drying technique
por: Daman, Zahra, et al.
Publicado: (2014)

Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery
por: Liang, Wanling, et al.
Publicado: (2018)

Optimizing Spray-Dried Porous Particles for High Dose Delivery with a Portable Dry Powder Inhaler
por: Son, Yoen-Ju, et al.
Publicado: (2021)

PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells
por: Su, Wen-Pin, et al.
Publicado: (2012)

Fate of Tableted Freeze-Dried siRNA Lipoplexes in Gastrointestinal Environment
por: Rehman, Asad Ur, et al.
Publicado: (2021)

The Use of a Three-Fluid Atomising Nozzle in the Production of Spray-Dried Theophylline/Salbutamol Sulphate Powders Intended for Pulmonary Delivery
por: Focaroli, Stefano, et al.
Publicado: (2020)

Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA
por: Capel, Victoria, et al.
Publicado: (2018)

Inhaled siRNA Formulations for Respiratory Diseases: From Basic Research to Clinical Application
por: Fan, Yulin, et al.
Publicado: (2022)

Moisture-Resistant Co-Spray-Dried Netilmicin with l-Leucine as Dry Powder Inhalation for the Treatment of Respiratory Infections
por: Cui, Yingtong, et al.
Publicado: (2018)

The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation
por: Kwon, Yong-Bin, et al.
Publicado: (2020)

In vivo pharmacokinetic and pharmacodynamic study of co-spray-dried inhalable pirfenidone microparticles in rats
por: Kang, Ji-Hyun, et al.
Publicado: (2022)

Acid-Sensitive Sheddable PEGylated PLGA Nanoparticles Increase the Delivery of TNF-α siRNA in Chronic Inflammation Sites
por: Aldayel, Abdulaziz M, et al.
Publicado: (2016)

p66shc siRNA-Encapsulated PLGA Nanoparticles Ameliorate Neuropathic Pain Following Spinal Nerve Ligation
por: Shin, Nara, et al.
Publicado: (2020)

Inhalable, Spray-Dried Terbinafine Microparticles for Management of Pulmonary Fungal Infections: Optimization of the Excipient Composition and Selection of an Inhalation Device
por: Almansour, Khaled, et al.
Publicado: (2021)

Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols
por: Lee, Hyo-Jung, et al.
Publicado: (2016)

Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects
por: Xu, You, et al.
Publicado: (2021)

Preparation and Characterization of a Dry Powder Inhaler Composed of PLGA Large Porous Particles Encapsulating Gentamicin Sulfate
por: Shiehzadeh, Farideh, et al.
Publicado: (2019)

Attenuation of fibrosis in vitro and in vivo with SPARC siRNA
por: Wang, Jiu-Cun, et al.
Publicado: (2010)

Nebulization of siRNA for inhalation therapy based on a microfluidic surface acoustic wave platform
por: Cortez-Jugo, Christina, et al.
Publicado: (2022)

Nanoemulsion Co-Loaded with XIAP siRNA and Gambogic Acid for Inhalation Therapy of Lung Cancer
por: Xu, Minhao, et al.
Publicado: (2022)

On an Improved Apparatus for Spray Inhalations
por: Adams, James
Publicado: (1879)

p47phox siRNA-Loaded PLGA Nanoparticles Suppress ROS/Oxidative Stress-Induced Chondrocyte Damage in Osteoarthritis
por: Shin, Hyo Jung, et al.
Publicado: (2020)

CRIF1 siRNA-Encapsulated PLGA Nanoparticles Suppress Tumor Growth in MCF-7 Human Breast Cancer Cells
por: Piao, Shuyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hrqum3op43ts55btnrq84o8j02