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The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain

The coronavirus M protein, the most abundant coronaviral envelope component, is invariably glycosylated, which provides the virion with a diffuse, hydrophilic cover on its outer surface. Remarkably, while the group 1 and group 3 coronaviruses all have M proteins with N-linked sugars, the M proteins...

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Detalles Bibliográficos
Autores principales: de Haan, Cornelis A.M, de Wit, Marèl, Kuo, Lili, Montalto-Morrison, Cynthia, Haagmans, Bart L, Weiss, Susan R, Masters, Paul S, Rottier, Peter J.M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science (USA). 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126936/
https://www.ncbi.nlm.nih.gov/pubmed/12919744
http://dx.doi.org/10.1016/S0042-6822(03)00235-6