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The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain
The coronavirus M protein, the most abundant coronaviral envelope component, is invariably glycosylated, which provides the virion with a diffuse, hydrophilic cover on its outer surface. Remarkably, while the group 1 and group 3 coronaviruses all have M proteins with N-linked sugars, the M proteins...
Autores principales: | de Haan, Cornelis A.M, de Wit, Marèl, Kuo, Lili, Montalto-Morrison, Cynthia, Haagmans, Bart L, Weiss, Susan R, Masters, Paul S, Rottier, Peter J.M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science (USA).
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126936/ https://www.ncbi.nlm.nih.gov/pubmed/12919744 http://dx.doi.org/10.1016/S0042-6822(03)00235-6 |
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