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Fat(al) attraction: Picornaviruses Usurp Lipid Transfer at Membrane Contact Sites to Create Replication Organelles

All viruses that carry a positive-sense RNA genome (+RNA), such as picornaviruses, hepatitis C virus, dengue virus, and SARS- and MERS-coronavirus, confiscate intracellular membranes of the host cell to generate new compartments (i.e., replication organelles) for amplification of their genome. Repli...

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Detalles Bibliográficos
Autores principales: van der Schaar, Hilde M., Dorobantu, Cristina M., Albulescu, Lucian, Strating, Jeroen R.P.M., van Kuppeveld, Frank J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126954/
https://www.ncbi.nlm.nih.gov/pubmed/27020598
http://dx.doi.org/10.1016/j.tim.2016.02.017