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Synthesis and SAR studies on azetidine-containing dipeptides as HCMV inhibitors
SAR studies on an azetidine-containing dipeptide prototype inhibitor of HCMV are described. Three series of structurally modified analogues, involving substitutions at the N- and C-terminus, and at the C-terminal side-chain were synthesized and evaluated for antiviral activity. Aliphatic or no subst...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127091/ https://www.ncbi.nlm.nih.gov/pubmed/21256035 http://dx.doi.org/10.1016/j.bmc.2010.12.052 |