SARS-CoV 3CL(pro) inhibitory effects of quinone-methide triterpenes from Tripterygium regelii

Quinone-methide triterpenes, celastrol (1), pristimerin (2), tingenone (3), and iguesterin (4) were isolated from Triterygium regelii and dihydrocelastrol (5) was synthesized by hydrogenation under palladium catalyst. Isolated quinone-methide triterpenes (1–4) and 5 were evaluated for SARS-CoV 3CL(p...

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Detalles Bibliográficos
Autores principales: Ryu, Young Bae, Park, Su-Jin, Kim, Young Min, Lee, Ju-Yeon, Seo, Woo Duck, Chang, Jong Sun, Park, Ki Hun, Rho, Mun-Chual, Lee, Woo Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127101/
https://www.ncbi.nlm.nih.gov/pubmed/20167482
http://dx.doi.org/10.1016/j.bmcl.2010.01.152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127101/
https://www.ncbi.nlm.nih.gov/pubmed/20167482
http://dx.doi.org/10.1016/j.bmcl.2010.01.152

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