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The hepatitis E virus ORF1 ‘X-domain’ residues form a putative macrodomain protein/Appr-1″-pase catalytic-site, critical for viral RNA replication
The hepatitis E virus (HEV) ORF1 gene encodes the non-structural polyprotein wherein the ‘X-domain’ still remains poorly defined. Cellular X-domain associated macrodomain protein/ADP-ribose-1″-monophosphatase (Appr-1″-pase) activities are also reported in coronaviruses (CoV), including identificatio...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier B.V.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127128/ https://www.ncbi.nlm.nih.gov/pubmed/25870943 http://dx.doi.org/10.1016/j.gene.2015.04.026 |