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Characterization of the first angiotensin-converting like enzyme in bacteria: Ancestor ACE is already active

Angiotensin-converting enzyme (ACE) is a metallopeptidase that converts angiotensin I into angiotensin II. ACE is crucial in the control of cardiovascular and renal homeostasis and fertility in mammals. In vertebrates, both transmembrane and soluble ACE, containing one or two active sites, have been...

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Detalles Bibliográficos
Autores principales: Rivière, Guillaume, Michaud, Annie, Corradi, Hazel R., Sturrock, Edward D., Ravi Acharya, K., Cogez, Virginie, Bohin, Jean-Pierre, Vieau, Didier, Corvol, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127174/
https://www.ncbi.nlm.nih.gov/pubmed/17597310
http://dx.doi.org/10.1016/j.gene.2007.05.010